Superbug Slayer: New Class of Antibiotics Proves Potent Against Multi-Drug Resistant Bacteria
scitechdaily.com
A new class of antibiotics capable of combating multi-drug resistant bacteria and treating bloodstream infections in mice has been unveiled by Uppsala University scientists. Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resista

This study describes the identification of an antibiotic class acting via LpxH, involved in lipopolysaccharide synthesis having potent in vivo efficacy against bloodstream infections caused by the critical Gram-negative pathogens E. coli and Klebsiella pneumoniae. Further development of this class of antibiotics could make an important contribution to the ongoing struggle against antibiotic resistance.

https://www.pnas.org/doi/10.1073/pnas.2317274121 (open access)